Author

Hongchen Zhang

2 papers indexed here

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Open access Sep 2026

Disrupting the BEX4-Mediated DNA Repair Rheostat with a Novel Inhibitor Suppresses Stemness and Enhances Chemosensitivity in Hepatoblastoma.

Cisplatin resistance in hepatoblastoma (HB) is a major therapeutic barrier. Emerging evidence suggests that cancer cells can activate DNA double-strand break repair pathways to evade chemotherapy-induced apoptosis and sustain stemness; however, the mechanisms underlying cisplatin resistance in HB remain poorly understo...

Ze-Yu Yan, Qian Wang, Jing Li et al. · Pharmacological Research · 0 citations

Open access Aug 2026

Engineered Xenogeneic Bone Scaffold with IL‐10 Nanodelivery System: Immunomodulation and BMSC Fate Programming for Skull Defect Repair

A multifunctional composite integrating antigen‐extracted xenogeneic scaffold, IL‐10‐loaded mesoporous polydopamine nanoparticles (MPDA@IL‐10), and autologous bone marrow‐derived mesenchymal stem cells (BMSCs) offers a translatable route to skull repair.

Wei-Hao Lv, Lei Zhang, F. Fei et al. · Advancement of science · 0 citations