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Hongmei Li

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Open access Jul 2026

Total flavonoids from Ageratum conyzoides synergize with docetaxel to induce ferroptosis in prostate cancer cells via the NRF2/SLC7A11/GPX4 signaling pathway.

TFG enhances the antitumor effect of DTX in prostate cancer cells by inhibiting the NRF2/SLC7A11/GPX4 axis, inducing lipid peroxidation, and triggering mitochondria-associated ferroptosis, providing a strong mechanistic rationale for developing TFG as a natural chemosensitizer for prostate cancer therapy, particularly...

Huili Liu, Ze-Yan Lin, Jiawang Guo et al. · 0 citations

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