Jul 2026
PLIN3 knockdown enhances T cell-mediated cytotoxicity in non-small cell lung cancer via autophagy-dependent PD-L1 degradation.
It is shown that targeting PLIN3 can induce autophagy, which promotes the degradation of PD-L1, ultimately leading to enhanced activation of T cells and an innovative approach to enhance the efficacy of immunotherapy in lung cancer.
Hanqiong Zhou, S. Fan, Min Ouyang et al.
· International Immunopharmaco... · 0 citations