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Author

Hongshan Xie

2 papers indexed here

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Aug 2026

Photodynamic activity of a mitochondria-localized G-quadruplex-responsive fluorescent ligand: Cellular effects and photo-enhanced cytotoxicity.

Mitochondrial localization concentrates photosensitizing molecules near redox-sensitive organelles. In this study, we investigated SPN, a mitochondria-targeted G-quadruplex (G4)-responsive ligand. Photochemical characterization confirmed that SPN generates robust light-triggered ROS and exhibits photooxidative activity...

Ya-Kun Wang, Jia-Peng Dong, Hongshan Xie et al. · 0 citations
Review Aug 2026

Organic photosensitizers for antifungal therapy: structural diversity and emerging applications.

Drug-resistant and biofilm-associated fungal infections remain difficult to treat with conventional antifungals. Antimicrobial photodynamic therapy (aPDT) uses light-activated organic photosensitizers to generate multi-target oxidative damage with spatiotemporal control. To establish how molecular design governs antifu...

Wei-Xuan He, Zi-Hao Liang, Hongshan Xie et al. · 0 citations

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