Open access
Aug 2026
MFN2 inhibits colorectal cancer tumorigenesis by regulating glycolysis through TRIM21-mediated PFKP stability.
BACKGROUND Colorectal cancer (CRC) is the third most common gastrointestinal cancer in terms of morbidity and mortality worldwide. Reprogramming of glucose metabolism will directly affect the energy supply pattern of tumor cells and determine their malignant biological behavior. Mitofusin-2 (MFN2) has been shown to be...
Huiyuan Jiang, Hongwei Guo, Yan Wang et al.
· Molecular Immunology · 0 citations