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Author

Hongxia Chen

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Open access Aug 2026

PDK1/AKT signaling is involved in the anti-tumor effect of gramine and cisplatin chemoresistance in ovarian cancer cells

Ovarian cancer (OC) remains one of the most lethal gynecologic malignancies, with limited therapeutic options and poor long-term prognosis. Gramine, an indole alkaloid predominantly derived from the rhizomes of Arundo donax L., has demonstrated antitumor activity in various cancer types; however, its effects and mechan...

Hai-Yan Wang, Ruiming Zheng, Bujun Wang et al. · 0 citations

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