Open access
Jul 2026
High-throughput bead-based cytokine profiling reveals dynamic immune signatures and identifies candidate exploratory biomarkers in CAR-T therapy
Chimeric antigen receptor T-cell (CAR-T) therapy has revolutionized the treatment of refractory B-cell malignancies, yet severe cytokine release syndrome (CRS) and unpredictable long-term outcomes remain major clinical challenges. Here, we developed a rapid, scalable, 96-well plate-based strategy for the high-throughpu...
Keyuan Pu, Wanying He, Jiayi Feng et al.
· Chemical Science · 0 citations