Modeling the FLASH effect for ion beams using a microdosimetry-based model
To develop a microdosimetry-informed modeling framework for predicting the ion-beam FLASH sparing effect (FSE) by coupling time-dependent oxygen depletion–recovery kinetics with oxygen-modulated radiosensitivity parameters, and to quantify how FSE varies with dose rate, oxygen tension, and beam quality (LET and dose-me...