Hope H. G. Gandu

CRISPR/Cas9-Mediated Knockout of ZFP36L1 Impairs Cell Proliferation, Alters Cell-Cycle Progression, and Enhances DNA Damage Responses in MDA-MB-231 Triple-Negative Breast Cancer Cells

Background Zinc finger protein 36-like 1 (ZFP36L1) is an AU-rich element-binding RNA-binding protein that regulates post-transcriptional gene expression and has been implicated in tumor progression, cell-cycle regulation, and DNA damage responses. However, its functional role in triple-negative breast cancer (TNBC) rem...