Open access
Oct 2026
The genetic landscape of RAG deficiency: Novel and founder variants in a large Algerian cohort
This study characterizes RAG1/RAG2 deficiency, a severe inherited immune disorder, in the largest reported cohort from a North African country. Two founder mutations explain most cases, yet limited transplant access drives high mortality, highlighting the need for newborn screening.
Brahim Belaid, Ko-On-Wing Chan, J. Stoddard et al.
· Journal of human immunity · 0 citations