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Hsiao-Chu Hsu

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Aug 2026

Vincristine enhances doxorubicin cardiotoxicity in human iPSC-derived cardiomyocytes: Partial attenuation by SGLT2 inhibition.

BACKGROUND Doxorubicin is a well-known cardiotoxic chemotherapeutic agent. Whether its combination with vincristine exacerbates cardiotoxicity and the underlying mechanisms remains unclear. METHODS Human induced pluripotent stem cell derived cardiomyocytes (iPSC-CMs) were treated with doxorubicin, vincristine, or bot...

Hsien-Yuan Chang, Hsiao-Chu Hsu, Yi-Hsien Fang et al. · 0 citations

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