Open access
Oct 2026
Structure-Based Identification of Potential Toll-Like Receptor 3 Agonists for Anti-HBV Applications
Hepatitis B virus (HBV) infection remains a major global public health burden, primarily due to the persistence of covalently closed circular DNA (cccDNA) in infected hepatocytes. Toll-like receptor 3 (TLR3) has been suggested to be a promising therapeutic target, as its activation stimulates innate immune responses th...
Szu-Hung Chen, Ming-Rui Chang, Yih Ho et al.
· Biophysica · 0 citations