Author

Hu-Cheng Zhu

3 papers indexed here

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Open access Oct 2026

Kaurepenoid A, a 2-nor-ent-kaurane diterpenoid with P-glycoprotein-mediated reversal of multidrug resistance activity from the fungus Bipolaris sp.

Chemical research on the fungus Bipolaris sp. led to the identification of seven ent-kaurane diterpenoids, kaurepenoids A-G (1-7), marking the first isolation of such diterpenoids from this genus. Kaurepenoids A-F (1-6) represent the first 2-nor-ent-kaurane diterpenoids with a fused 5/6/6/5 tetracyclic ring system. Kau...

Yong Shen, Nan-Jin Ding, Mei-Jia Zheng et al. · Chinese Journal of Natural M... · 0 citations

Open access Sep 2026

A new sesquiterpenoid and three other unusual compounds from Xylaria hypoxylon.

A new sesquiterpenoid and three other unusual compounds (1-4) along with four known compounds (5-8) were isolated and identified from the fungus Xylaria hypoxylon. Structures of compounds 1-4 with absolute configurations were elucidated by extensive NMR spectral analyses, X-ray crystallography, experimental ECD spectra...

P. Zhou, Zhen-Tong Ni, Jin-Yan Cai et al. · Fitoterapia · 0 citations

Open access Sep 2026

Structural and Mechanistic Basis of Dual Substrate Promiscuity in the Acyltransferase AntB Enables Late-Stage Diversification of Natural Products.

Biocatalytic regioselective acylation is a powerful strategy for diversifying natural products and optimizing their pharmacological properties. Compared with plant acyltransferases (ATs), bacterial tailoring ATs remain poorly understood. AntB from the antimycin pathway was previously reported to possess acyl-donor prom...

Meng-Meng Zheng, Yu-Han Dai, Xiang-Yu Li et al. · Angewandte Chemie · 0 citations