Open access
Jan 2026
Integrative Single‐Cell and Spatial Transcriptomics Identifies CRIP1+ Prehypertrophic Chondrocytes as Inflammatory Hubs and a Valuable Diagnostic Biomarker for Osteoarthritis
Osteoarthritis (OA) is a prevalent degenerative joint disease characterized by progressive cartilage destruction, yet the heterogeneity of transitional chondrocyte states and their contributions to pathogenesis remain incompletely understood. In this study, we constructed a single‐cell transcriptomic atlas of human kne...
Zi-Kang Xie, Yu Wang, Jinzhu Liu et al.
· Mediators of Inflammation · 0 citations