CDKL1 facilitates tumorigenesis and metastasis of bladder urothelial carcinoma by activating SIRT1/Wnt/β-catenin signaling.
Bladder urothelial carcinoma (BUC) is a common malignancy characterized by high recurrence and progression, and patients with advanced disease often have poor outcomes due to therapeutic resistance and limited targeted treatment options. In this study, we investigated the role of cyclin-dependent kinase-like 1 (CDKL1)...