Hua-Lei Wang

Functional characterization of terpene synthases from Dendrobium nobile provides insights into the biosynthesis of copaborneol, a proposed dendrobine precursor

Picrotoxane-type sesquiterpene alkaloids, including dendrobine, are characteristic constituents of Dendrobium nobile, but the enzymes that produce their proposed skeletal precursors remain incompletely characterized. Here, we combined tissue metabolite profiling with genome-guided screening and biochemical characteriza...