Open access
Oct 2026
Hemicyanine-Based Wash-Free Near-Infrared Fluorescent Probe for Imaging Amyloid-β Aggregates in Alzheimer’s Disease
By fine-tuning the amphiphilicity of a hemicyanine scaffold to place its log P within the appropriate range, P3 is identified as a wash-free NIRF probe for Aβ aggregates and provides a wash-free, high-affinity NIRF probe for Aβ imaging.
Xue-Qi Zhao, Run-Dong Liang, Yao Li et al.
· Molecules · 0 citations