Open access
Sep 2026
Synthesis of benzenesulfonamide derivatives reveals anti-CCSCs activity by regulating Wnt/β-catenin pathway.
BACKGROUND Colorectal cancer (CRC) has become one of the most common causes of cancer mortality worldwide. Accumulating studies suggest that the progressive up-regulation of Wnt/β-catenin signaling is a crucial hallmark of CRC, and this pathway is involved in the development and maintenance of colorectal cancer stem ce...
Xue-Yu Wang, Kai-Li Wang, Quan-Xing Zhong et al.
· Future Medicinal Chemistry · 0 citations