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Hua Yuan

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Open access Oct 2026

Source-resolved electroencephalogram microstates reveal opposing prefrontal-posterior dynamics and a candidate temporal-to-precuneus pathway in disorders of consciousness

Objective and circuit-level biomarkers of consciousness are urgently needed for disorders of consciousness. We recorded high-density electroencephalography from 33 patients with disorders of consciousness (17 vegetative state/unresponsive wakefulness syndrome, 16 minimally conscious state) and 19 healthy con...

Kun Li, Shi-Yu Zhang, Xu Hu et al. · 0 citations
Open access Sep 2026

Motor Cortex rTMS Alleviates Pain and Comorbid Depression After Spinal Cord Injury with a Correlate in M1 Intracortical Inhibition

Purpose Neuropathic pain (NP) after spinal cord injury (SCI) is a debilitating syndrome, yet current treatments demonstrate limited efficacy. This randomized, double-blind, sham-controlled study investigated the analgesic efficacy of high-frequency repetitive transcranial magnetic stimulation (rTMS) over the left prima...

Yi-Xing Lu, Kun Zhao, Xin-Yu Liu et al. · 0 citations
Open access Oct 2026

Drp1 in M1 layer V GABAergic neurons orchestrates rTMS-mediated motor restoration and analgesia after spinal cord injury

Spinal cord injury (SCI) leads to chronic motor and sensory deficits, with progressive secondary neurodegeneration posing a major therapeutic challenge. Although high-frequency repetitive transcranial magnetic stimulation (HF-rTMS) over the primary motor cortex (M1) shows therapeutic potential, its underlying cellular...

Xiao-Long Sun, Rui Zhao, Kun-Long Zhang et al. · 0 citations
Open access Sep 2026

Deep transcranial magnetic stimulation is superior to normal in motor-evoked potentials

Background: Deep transcranial magnetic stimulation (dTMS) using an H7 coil is widely applied in the treatment of several neurological diseases. However, whether dTMS with an H7 coil is superior to figure-of-eight coil transcranial magnetic stimulation (TMS) for neurophysiological assessment remains unclear. Methods: Th...

Wei Sun, Xiao Xi, Juan Li et al. · 0 citations
Open access Sep 2026

Single-Nucleus Transcriptomic Mapping Reveals Correlative Microglial Changes Associated with rTMS in the Motor Cortex After Spinal Cord Injury

The snRNA-seq analysis identifies M1 cortical microglial transcriptional and communication changes that correlate with SCI-induced NP and provides a hypothesis-generating preclinical foundation for future mechanistic studies targeting cortical microglia with rTMS.

Kun-Long Zhang, Xin-Jiang Yang, Rui-Bin Hou et al. · 0 citations
Open access Aug 2026

Positive association and shared genetic structure between cardiovascular diseases and osteoarthritis: Insights from cross-sectional study and genome-wide pleiotropic analysis

A positive association was observed between the prevalence of CVDs and OA, potentially explained by shared genetic factors, and Pathway assessment and multi-trait colocalization suggested that abnormal lipid metabolism may be a common cause of CVDs and OA.

Yuheng Lu, Dexi Hu, Fei Tian et al. · 0 citations

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