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Hua-Ze Zhu

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Open access Oct 2026

Tacrolimus attenuates BCL-2/BAX-mediated chondrocyte apoptosis and cartilage matrix degradation in experimental osteoarthritis

Osteoarthritis is a progressive whole-joint disease characterized by cartilage matrix degradation, synovial inflammation and impaired chondrocyte survival. Current pharmacological treatments mainly relieve symptoms and do not reliably prevent structural progression. Here, we investigated whether tacrolimus, a clinicall...

Hua-Ze Zhu, Yun Chen, B. Ruan et al. · 0 citations

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