Author

Huai-Tian Liu

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Open access Oct 2026

Δ133p53α, a senescence-inhibitory p53 isoform, attenuates accelerated aging in progeria mice

Research on progeria not only contributes to the development of treatments for the disease but also enhances our understanding of physiological aging. In a mouse model of Hutchinson-Gilford progeria syndrome (HGPS), transgenic expression of Δ133p53α, a senescence-inhibitory human p53 isoform, reduced the expression...

Leo Yamada, Huai-Tian Liu, Natalia von Muhlinen et al. · npj Aging · 0 citations

Open access Aug 2026

Single-cell profiling of peripheral blood mononuclear cells in diverse men with prostate cancer reveals a fatal disease-associated immune signature

Alterations in peripheral immunity may contribute to fatal prostate cancer and the excessive disease burden among African American (AA) men. Thus, we investigated peripheral immunity in prostate cancer patients in association with disease outcome and AA descent. We performed single-cell RNA and T cell receptor (TCR) se...

Huai-Tian Liu, Alexandra R. Harris, Tiffany H. Dorsey et al. · Cancer immunology research · 0 citations