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Open access Nov 2026

CD34+-selected stem cell boost for poor graft function after allogeneic hematopoietic stem cell transplantation: a large cohort study focusing on haploidentical transplantation.

Poor graft function (PGF) is a life-threatening complication after allogeneic hematopoietic stem cell transplantation (allo-HSCT). CD34+-selected stem cell boost has shown promise; however, data in the haploidentical setting and after failure of thrombopoietin receptor agonists (TPO-RAs) are limited. Patients who recei...

Y. He, Lin-Wei Shi, R. Ma et al. · 0 citations
Open access Oct 2026

Single-cell dissection of self-derived versus donor-derived T cell exhaustion niches in patients with acute myeloid leukemia

Summary Relapse remains the main cause of death in acute myeloid leukemia (AML), and T cell exhaustion is related to relapse in both non-allografting and allografting settings. However, differences in exhausted T cells (Tex) across different disease contexts remain incompletely understood. We performed single-cell RNA...

Chun-Zi Yu, Yu-Lun Chen, Xiao-Hui Zhang et al. · 0 citations

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