Review
Open access
Sep 2026
The impact of macrophage metabolism on idiopathic pulmonary fibrosis development and treatment prospectives
Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive fibrotic interstitial pneumonia of unknown etiology, in which macrophages serve as central orchestrators of the pathological microenvironment. During IPF progression, the alveolar macrophage pool undergoes a critical compositional shift: tissue-resident alve...
Guang-Yan Mu, Shan Chong, Jiu-Long Li et al.
· Frontiers in Immunology · 0 citations