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Huan-Zhi Wan

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Open access Sep 2026

PINK1–Associated Mitophagy Protects Against Cisplatin–Induced Ototoxicity by Regulating the Subcellular Distribution of ACSL4

Cisplatin–induced ototoxicity is a significant clinical issue linked to ferroptosis and mitophagy dysfunction. This study investigated how mitophagy regulates ferroptosis in cisplatin–induced hearing loss using cultured primary rat cochlear marginal cells in vitro and a C57BL/6J mouse model of cisplatin–induced ototoxi...

Ting Li, Wen-Ting Yu, Huan-Zhi Wan et al. · 0 citations

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