Open access
Jul 2026
Nuclear m6A Methylase METTL3 Drives Production of ITGβ4E to Exacerbate Heart Failure via SRSF3-Mediated Alternative Splicing of ITGβ4.
The m6A methylase METTL3 drives production of ITGβ4E to exacerbate HF via SRSF3-mediated alternative splicing of ITGβ4 mRNA, suggesting that alternative splicing of ITGβ4 may be a potential therapeutic target for HF.
Li Yao, Chao Liu, Jian Dong et al.
· The FASEB Journal · 0 citations