Role of dopaminergic projections from ventral tegmental area to paraventricular thalamus in heroin-induced behavioural sensitization of rats.
The ventral tegmental area (VTA) is involved in the behavioral sensitization to heroin, but the possible neural projections and molecular mechanisms remain unclear. Rats first underwent 8 days of heroin sensitization induction, followed by a 10-day drug-free period. Subsequently, a M5 muscarinic acetylcholine receptor...