Sep 2026
Lysosome-Targeted Iridium(III) Photosensitizers Activate the Mitophagy−Ferroptosis Axis to Boost Two-Photon Photoimmunotherapy Against Hypoxic Cisplatin-Resistant Tumors
A hypoxia-tolerant dinuclear photosensitizer that couples two-photon PDT to ferroptosis and systemic antitumor immune activation is established.
Hui Jiang, Qiaoshan Lie, Fa Wang et al.
· Journal of Medicinal Chemist... · 0 citations