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Hui-Lin Li

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Open access Sep 2026

Cryo-EM structures of autoinhibited and RNA-activated ZNFX1 helicase

Cryo-electron microscopy and biochemical analyses support a regulatory mechanism in which autoinhibited ZNFX1 exists as monomers or concentration-dependent higher-order oligomers, whereas RNA binding promotes structural remodeling and helicase activation.

Qing He, Feng Wang, F. Rassool et al. · 0 citations

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