Efficient production of highly bioactive interleukin-15 in the silkworm silk gland bioreactor.
Interleukin-15 (IL-15) is a pleiotropic cytokine that plays a key regulatory role in immune responses and inflammation by promoting the proliferation and survival of natural killer (NK) cells and CD8+ T cells. However, the large-scale production of bioactive recombinant human interleukin-15 (rhIL-15) remains challengin...