Frailty-Related Metabolic Signature in the Association Between Frailty and Coronary Artery Disease: Modification by Genetic Susceptibility.
BACKGROUND Frailty is associated with increased coronary artery disease (CAD) risk, but the circulating metabolic features underlying the frailty-CAD relationship and their interplay with genetic susceptibility remain unclear. This study aimed to identify a frailty-related metabolic signature, assess its estimated medi...