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Author

Hui-Peng Zhang

2 papers indexed here

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Sep 2026

Engineered cryo-shocked tumor cells recruit T cells for lung cancer immunotherapy.

Immune checkpoint blockade has transformed cancer therapy, yet its efficacy against solid tumors remains constrained by poor T cell infiltration and an immunosuppressive tumor microenvironment. Achieving localized and sustained chemokine signaling without systemic immune toxicity remains a central unmet challenge for c...

Hui-Heng Feng, Feng Liu, Ze-Sheng Cheng et al. · 0 citations
Sep 2026

Delivery of CAR T Cells in a Magnesium-Functionated Hydrogel Boosts Peritoneal Metastasis Treatment.

Chimeric antigen receptor (CAR) T cells show limited efficacy in solid tumors due to suppressive factors in the tumor microenvironment. In this study, we identified extracellular magnesium (Mg2+) as a pharmacologically modulable regulator of CAR T activity. Mg2+ supplementation increased early activation and augmented...

Jun-Lin Li, Xu-Tao Liu, En Ren et al. · 0 citations

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