Aug 2026
Identifying GADD45A as a potential R-loop regulator in sepsis via machine-learning and multi-omics analysis.
BACKGROUND Sepsis is a life-threatening syndrome characterized by dysregulated immune responses, while the molecular basis of immune dysfunction remains unclear. Increasing evidence suggests that R-loop accumulation and DNA damage may contribute to immune disorders, but their roles in sepsis have not been systematicall...
Min Chen, Jie-Xiang Kang, Shi-Ying He et al.
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