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Open access Oct 2026

Performance Characteristics for Flow Cytometric Enumeration of Peripheral Blood Lymphocyte Subsets under Harmonized Laboratory Conditions: A Multicenter Study.

BACKGROUND Flow cytometric enumeration of peripheral blood lymphocyte subsets (EPBLS) is essential for disease management, yet standardized validation criteria are lacking. We defined key performance characteristics under harmonized conditions to support criteria development. METHODS 205 whole blood samples and 54 qu...

Lin Xiao, Yuan Wang, Yi Li et al. · 0 citations
Review Open access Jul 2026

Cholesterol metabolism reprogramming: shaping tumor immunity and immunotherapy

A deeper understanding of cholesterol and its metabolite dynamics within the tumor microenvironment, as well as their crosstalk with other signaling networks, will not only aid in optimizing current immunotherapeutic approaches but also provide a crucial conceptual foundation for developing novel combination strategies...

Jingzhi Meng, Yue Tan, Shang Chen et al. · 0 citations

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