Open access
Jul 2026
Glymphatic dysfunction mediates inflammation-driven vascular burden and cognitive decline in cerebral small vessel disease.
BACKGROUND Cerebral small vessel disease (CSVD) is increasingly recognized as a disorder involving microvascular dysfunction, impaired perivascular clearance, and inflammatory processes. However, how systemic inflammatory burden, neurovascular coupling (NVC), glymphatic MRI markers, vascular lesion burden, and cognitio...
Yi-Lei Chen, Jie-Jing Zhang, Yingjie Kang et al.
· Neurobiology of Disease · 1 citation