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Author

Hui-Yu Tai

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Open access Oct 2026

U-shaped association between left ventricular ejection fraction and short-term mortality in adults with sepsis: a retrospective cohort study using MIMIC-IV and MIMIC-IV-ECHO

Cardiac dysfunction is common in sepsis, but the prognostic meaning of the left ventricular ejection fraction (LVEF) is uncertain and may be non-linear. We used newly released open echocardiographic data to characterise that shape. Retrospective cohort study of adults meeting Sepsis-3 criteria in the linke...

Lu-Jun Shao, Hui-Yu Tai, Yue Li et al. · 0 citations
Review Open access Aug 2026

Emerging microbiome–mitochondria crosstalk in host defense and infectious diseases: mechanistic insights into NLRP3 inflammasome activation and mtDNA-mediated immunomodulation

These investigations emphasize the emerging mechanistic significance of microbiota-induced modulation of mitochondrial function in host defense mechanisms, thereby illuminating potential therapeutic approaches that focus on microbial composition, mitochondrial dynamics, and inflammasome signaling to alleviate infectiou...

Xinxing Lu, Wenbin Sun, Daowei Zhang et al. · 1 citation

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