Author

Hui Zhang

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Open access Sep 2026

Targeting the YAP‐BST2 Axis Overcomes Intrinsic Anti‐PD‐1 Resistance in Metastatic Gastric Cancer

YAP activation, cooperating with TP53 loss, fuels metastatic GC and immunotherapy resistance via BST2 induction, and this “double‐hit” alone suffices to recapitulate human refractory GC.

Wei-Hong Zhang, Shi-Long Wang, Meng Wang et al. · Advancement of science · 0 citations