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Hui-Zi Chen

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Aug 2026

The transcriptional regulator CasR controls mycobacterial antioxidant defense and biofilm formation via multiple direct targets.

This study establishes CasR as a pleiotropic transcriptional regulator that directly controls multiple antioxidant genes, including cyp144 and katGI, in mycobacteria, and identifies CasR and Cyp144 as potential targets for the development of anti-tuberculosis drugs.

Hui-Zi Chen, Yuan-Peng Li, Jiachen Zheng et al. · 0 citations

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