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Huichang Ryu

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Open access Jul 2026

Heterologous production of tungsten-dependent formate dehydrogenase I from Methylorubrum extorquens in Escherichia coli reveals α-subunit maturation as the major bottleneck

The α-subunit was the major bottleneck in Me-FDH1 production and was defined as the key bottleneck for Me-FDH1 production in E. coli and provides a roadmap for engineering hosts for tungsten-containing enzymes.

N. Nguyen, Huichang Ryu, Joon Young Park et al. · 0 citations

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