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Huijie Cao

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Aug 2026

Chemo-enzymatic synthesis of a flexible spacer-modified β-sitosterol derivative with preserved cholesterol-lowering activity.

BACKGROUND Phytosterols, particularly β-sitosterol, exhibit well-recognized cholesterol-lowering activity; however, their practical application is constrained by rigid molecular structures and limited structural tunability. Rational molecular modification combined with the introduction of flexible linkers may provide a...

Ya-Qing Zhang, Shilin Hu, Huijie Cao et al. · 0 citations

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