Spatial profiling of proteins and protein interactions facilitates understanding of cell functions within tissues and is essential for studies in signaling, immunity, and cancer. We present spatial proximity sequencing (Sprox-seq) for simultaneous profiling of surface proteins, protein complexes, and mRNAs, recording t...
Huili Wang, Junjie Xia, P. Rahman et al.· Cell· 0 citations
Simple Summary Breast cancer treatment is guided by three molecular biomarkers—estrogen receptor (ER), progesterone receptor (PR), and HER2—typically measured by immunohistochemistry (IHC), a process that requires additional staining, time, and specialist review. Whole-slide image (WSI) foundation models are large pre-...
S. Atiya, Jiayou Liang, Kwaku Ofori-Atta et al.· Cancers· 0 citations
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