Author

Huili Ye

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Open access Aug 2026

Targeting MEST using cobicistat as a therapeutic strategy for gastric cancer through suppressing NF-κB signaling

Cobicistat, a candidate MEST-inhibitory compound, exhibits favorable preclinical efficacy and safety, providing a promising candidate for targeted GC therapy, and functions as a key oncoprotein driving GC progression via NF-κB activation.

Hong-Tai Cao, Huili Ye, Wen-Tao Zhang et al. · Frontiers in Oncology · 0 citations

Review Open access Jul 2026

ATF4 orchestrates cancer hallmarks: Stress adaptation, metabolic reprogramming and immune suppression

The molecular frameworks by which ATF4 integrates stress signals from the endoplasmic reticulum, oxidative stress, and nutrient deprivation to orchestrate metabolic reprogramming and immune evasion are dissected.

Zhiying Peng, Tong Xu, Z. Xia et al. · iScience · 0 citations