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Sponsored AI Networking Cookbook: Practical recipes for AI-assisted network automation and development AI Networking Cookbook: Practical recipes for AI-assisted network automation and development

Author

Huiqin Xu

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Open access Aug 2026

DYNAMIC CONFORMATIONS IN THE ACTIVATION OF PINK1 KINASE

Under mitochondrial stress, the mitochondrial kinase PINK1 is activated to phosphorylate ubiquitin, which in turn recruits the E3 ligase Parkin, thereby initiating clearance of damaged mitochondria. Dysregulation of the PINK1–Parkin signaling pathway is associated with early- onset autosomal recessive Parkinson’s disea...

Huiqin Xu, Xin-Yang Liu, Yan Jiang et al. · 0 citations
Open access Aug 2026

MOLECULAR BASIS FOR PINK1 MATURATION

A general mechanism for PINK1 recognition by the HSP90α/CDC37/FKBP51 chaperone complex is revealed and a potential approach for upregulating PINK1 activity, which is impaired in PD is suggested.

Junrong Xue, Huiqin Xu, Yanfeng Zhang et al. · 0 citations

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