Unexplained Colistin Resistance in Klebsiella pneumoniae: Insights into sRNA-Mediated Post-Transcriptional Regulation.
Colistin is a last-resort antibiotic used to treat infections caused by multidrug-resistant Gram-negative pathogens, including Klebsiella pneumoniae. Resistance to colistin can be explained by canonical mechanisms involving chromosomal mutations that activate lipid A modification pathways or by acquisition of plasmid-m...