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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

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Hung-Han Huang

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Sep 2026

Abstract B099: Tumor progression locus 2 kinase drives pancreatic cancer immune evasion through a MYBL2-CXCL10 signaling axis

Pancreatic ductal adenocarcinoma (PDAC) is characterized by a chronically inflamed tumor microenvironment (TME) driven by persistent activation of innate inflammatory signaling. Tumor progression locus 2 (TPL2; MAP3K8) is a serine/threonine kinase downstream of KRAS that activates both MAPK and NF-κB signaling; howev...

Hua-Ping Li, Yu-Tong Geng, Hung-Han Huang et al. · 0 citations

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