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Sponsored AI Networking Cookbook: Practical recipes for AI-assisted network automation and development AI Networking Cookbook: Practical recipes for AI-assisted network automation and development

Author

Hung T. Nguyen

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Open access Oct 2026

Deciphering the Structure−Activity Relationships Underpinning the Linkerology of Bivalent EGFR Inhibitors

Linking small molecules that bind adjacent sites on a target is a promising strategy for developing compounds with tight binding affinities. ATP-allosteric bivalent inhibitors (AABIs) of the epidermal growth factor receptor (EGFR) have provided new insights into efficient linker design where large potency gains can b...

Kishan B. Patel, I. A. Akinwumi, Tess M. Weber et al. · 0 citations
Review Open access Sep 2026

Beyond RNA/DNA: exploring the emerging role of Poly(ADP-ribose): structure, function, and condensate formation

This review highlights the key differences between PAR and nucleic acids, emphasizing why PAR could be an especially effective scaffold, and compares PAR structures with nucleic acids, and examines the physicochemical factors that influence PAR structure and its condensate formation.

Lipika Baidya, Hung T. Nguyen · 0 citations
Aug 2026

Molecular origins of heterogeneous aging and spatial organization in RNA condensates

It is demonstrated that aging is driven by sequence-encoded base pairing that favors RNA expansion, alignment and the formation of a dense interchain interaction network, establishing RNA sequence patterning as a key determinant not only of phase separation but also of condensate aging and spatial organization.

Dibyajyoti Mohanta, He-Yang Zhang, D. Thirumalai et al. · 0 citations

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