Snail superfamily transcriptional repressors Scratch1 and 2 are essential for maintenance of retinal ganglion cells and normal visual function.
Scratch1 and Scratch2 (Scrt1/2) of the Snail superfamily transcriptional repressors are evolutionarily well-conserved from nematodes to humans and are predominantly expressed in the developing central nervous system. However, the in vivo functions and underlying mechanisms of Scratch remain unclear because of the lack...