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Author

Hyejung Min

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Open access Sep 2026

Chemical induction and reversal of photoreceptor dystrophy in retinal organoids.

Activating transcription factor 6 (ATF6) controls a signal transduction pathway of the unfolded protein response (UPR). Loss-of-function ATF6 mutations cause inherited photoreceptor diseases. Ceapin-A7 is a non-toxic, cell-permeable small molecule that selectively inhibits ATF6. We investigated how ATF6 inhibition impa...

Allyssa Bradley, Hyejung Min, Soyoung Park et al. · 0 citations

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