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Author

Hyun-Hee Koh

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Open access Sep 2026

CD28-ICOS costimulation enhances the therapeutic efficacy of L1CAM-targeted CAR-T cells against ovarian and gastric cancers

Abstract Background Ovarian and gastric cancers are associated with poor prognosis and derive limited benefit from current therapies, highlighting the need for novel immunotherapeutic approaches. The L1 cell adhesion molecule (L1CAM) is aberrantly expressed in several types of solid tumors and is associated with aggres...

X. Che, Un-Jung Yun, Junsub Lee et al. · 0 citations
Aug 2026

Batch Effects in Tumor-Only NGS Panel Sequencing and Implications for CNV Detection.

A strategy is presented that calculates the median and median absolute deviation of gene-level fold changes across all samples within each sequencing batch and incorporates these measures into the result interpretation, providing batch-level reference metrics and supporting more reliable interpretation in comprehensive...

Chung Lee, Sejoon Lee, Hyun-Hee Koh et al. · 0 citations

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