Author

Hyun-Sik Yang

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Open access Oct 2026

Longitudinal associations of hormone therapy and depressive symptoms in cognitively unimpaired older women

Women are disproportionately affected by depressive disorders relative to men, and mid-life differences like menopause can exacerbate symptoms. Hormone therapy (HT) is a common treatment to ease menopause transitions, including vasomotor and depressive symptoms, that may occur due to menopause-related hormonal ch...

Kelly A. Lopez Garcia, H. Klinger, Catherine E. Munro et al. · BMC Medicine · 0 citations

Open access Aug 2026

Association Between Alzheimer Pathology, Sleep, and Cognition in Patients With Late-Onset Unexplained Epilepsy

Findings support the utility of plasma p-tau217 as a biomarker in this population and underscore the role of sleep processes in the relationship between neurodegenerative pathology and cognition in older adults with epilepsy.

R. Sarkis, Hyun-Sik Yang, Lei Liu et al. · Neurology · 0 citations

Open access Jul 2026

Prognostic Value of Blood-Based P-Tau217 Levels for Progression to Cognitive Impairment.

Higher plasma p-tau217 levels were consistently associated with increased risk of clinical progression and accelerated cognitive decline, and support the potential of p-tau217 for prognostic model development, with direct implications for future trial design.

R. Buckley, D. Townsend, C. Birkenbihl et al. · Journal of the American Medi... · 3 citations