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Author

Hyun-Suk Jung

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Sep 2026

Structural insights into actin severing and capping by gelsolin.

Gelsolin is a calcium-dependent actin-binding protein composed of six homologous domains (G1-G6) and regulates cytoskeletal dynamics. Here, we present the 2.89 Å cryo-EM structure of two G1-G3s bound to a four-subunit actin filament fragment formed after phalloidin-stabilized filamentous-actin (F-actin) was treated wit...

Han-ul Kim, Hyun-Suk Jung · 0 citations

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